SOX9 GOVERNS DIFFERENTIATION STAGE-SPECIFIC GENE EXPRESSION IN GROWTH PLATE CHONDROCYTES VIA DIRECT CONCOMITANT TRANSACTIVATION AND REPRESSION.

SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.

Cartilage and endochondral bone development require SOX9 activity to regulate chondrogenesis, chondrocyte proliferation, and transition to a SILVER SHAMPOO non-mitotic hypertrophic state.The restricted and reciprocal expression of the collagen X gene, Col10a1, in hypertrophic chondrocytes and Sox9 in immature chondrocytes epitomise the precise spat

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A moderate spinal contusion injury in rats alters bone turnover both below and above the level of injury with sex-based differences apparent in long-term recovery

Spinal cord injury (SCI) leads to significant sublesional bone loss and high fracture rates.While loss of mechanical loading plays a significant role in SCI-induced bone loss, animal studies have demonstrated mechanical loading alone does not fully account for loss of bone following SCI.Indeed, we have shown that bone loss occurs below the level of

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Writing Music Therapy

Communicating about music therapy is problematic because discursive language fails to convey Plunger Cutters the nonverbal, embodied essence of experience.I explore the emergence of this problem in the music therapy literature.I discuss the scholarship of phenomenological writing.I provide examples of nondiscursive music therapy writing.I introduce

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Histopathological Comparative Analysis between Syndromic and Non-Syndromic Odontogenic Keratocysts: A Retrospective Study

(1) Background: The aim of this study was to compare the histopathological features of syndromic and non-syndromic odontogenic keratocysts (OKs) using conventional and Confocal Laser Scanning Microscopy (CLSM) with their biological behaviour.(2) Methods: Data from the medical records of 113 patients with histological diagnosis of Shooting Seat Stic

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Investigating Black-Box Model for Wind Power Forecasting Using Local Interpretable Model-Agnostic Explanations Algorithm

Wind power forecasting (WPF) is important for safe, stable, and reliable integration of new energy technologies into power systems.Machine learning (ML) algorithms have recently attracted increasing attention in the field of WPF.However, opaque decisions and lack of trustworthiness of black-box models for WPF could cause scheduling risks.This study

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